Home » Design Of Enzyme Inhibitors As Drugs by Merton Sandler
Design Of Enzyme Inhibitors As Drugs Merton Sandler

Design Of Enzyme Inhibitors As Drugs

Merton Sandler

Published March 30th 1989
ISBN : 9780192615374
Hardcover
832 pages
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 About the Book 

This book presents authoritative accounts of the major target enzymes and their inhibitors which are currently the focus of research. The introductory chapters describe the underlying physical and chemical processes of enzyme inhibition and theMoreThis book presents authoritative accounts of the major target enzymes and their inhibitors which are currently the focus of research. The introductory chapters describe the underlying physical and chemical processes of enzyme inhibition and the general principles of inhibitor design using the many sophisticated and computer-based techniques that are now available. Subsequent chapters discuss in detail the wide range of individual target enzymes and inhibitors, emphasizing the factors which affect their usefulness in the clinical context: bioavailability, pharmacokinetics and side-effects.